2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS

Authors

  • Annalisa Aluigi
  • T. Posati
  • G. Sotgiu
  • R. Zamboni
  • G. Guidotti
  • M. Soccio
  • A. Munari
  • N. Lotti
  • M. Barbalinardo
  • F. Valle

Keywords:

wound dressing, drug delivery, keratin, electrospinning

Abstract

Regenerated wool keratin is a promising natural material for wound dressing. In the present study, keratin extracted from wool was blended with poly(butylene succinate) in 1,1,1,3,3,3-hexafluoro-2-propanol (blending ratio 50/50) and electrospun into nanofibrous mats. Compared to the pure poly(butylene succinate) nanofibres, the keratin based ones showed lower diameters, lower mechanical properties but an increased biodegradability, a delayed diclofenac release and increased bioactivity.

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Published

2019-08-13

Issue

2019: Autex

Section

Electrospinning

License

Copyright (c) 2019 Annalisa Aluigi, T. Posati, G. Sotgiu, R. Zamboni, G. Guidotti, M. Soccio, A. Munari, N. Lotti, M. Barbalinardo, F. Valle

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.