COMPARISON OF LACTATE, PYRUVATE AND POTASSIUM CONCENTRATION IN THE CARDIAC LYMPH AND, ARTERIAL AND CORONARY SINUS PLASMA IN DOGS

Abstract

Lactate (LA), pyruvate (PYR) and potassium (K)
concentration in the cardiac lymph were compared
with those in the arterial and coronary sinus plasma
in dogs. In each substance, there was a good
correlation between the plasma and cardiac lymph
level in the control period. In respect to LA and
PYR, the concentration in the cardiac lymph
correlated more with that in the arterial plasma
than in the coronary sinus one. During the infusion
of isoproterenol, LA and PYR in the plasma increased,
while K decreased. Each substance in the cardiac
lymph changed to the same degree as in the plasma
in mean values. Good correlation was also observed
between the arterial plasma and cardiac lymph level
during the administration of the agent. However,
there was no correlation of PYR between the
coronary sinus plasma and the cardiac lymph.
During the administration of dipyridamole LA in
the coronary sinus plasma increased and that in the
arterial plasma decreased. LA in the cardiac lymph
did decrease as in the arterial plasma. It is concluded
that the concentrations of LA, PYR and K in the
cardiac lymph can be changed depending upon
changes in those in the plasma and the former two
parameters seem to change depending upon those in
the arterial plasma rather than the coronary sinus
one.