ASPIRATION BIOPSY CYTOLOGY

J Zajicek

Abstract


After the presentation of the technique of the
aspiration biopsy and the mode of preparation and
staining of the smears, the author discusses the usefulness
and limitations of this procedure in the diagnosis
of benign and malignant lymph node lesions.
Studies on blastocytic transformation in short-term
tissue cultures in the presence of phytohaemagglutinin
have indicated that the cells are unimpaired by the
needling and/or the negative pressure used in the
aspiration. Since the patient experiences little discomfort
from fine needle biopsy, the aspiration biopsy
of lymph nodes can also be used for sampling cell
material in clinical research.
The problem of dissemination of tumor cells via the
needle track or efferent lymph or blood vessels is
also discussed. The use of fine needle aspiration
biopsy in diagnosis of malignant tumors does not
appear to involve a risk of tumor spread.


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