THE ORGANIZATION OF LYMPHOID TISSUE IN RELATION TO FUNCTION

Abstract

Organized lymphoid tissue is found in the thymus,
spleen, lymph nodes; lining the respiratory and
alimentary tracts; and also occurring at sites of
chronic inflammation. Apart from the thymus which
is involved in the regulation of T-cell function, the
other tissues are organized into T-cell and B-cell
areas. Lymphocytes in T-cell areas respond by proliferation
in cell-mediated immunity and by the production
of suppressor cells and helper cells for antibody
formation. B-cell areas are involved in the
humoral antibody response. B-cells are segregated
into lymph follicles where they form germinal