AMOEBOID MOVEMENT CONFIGURATION AND MITOTIC INDICES OF LYMPHOID CELLS FROM CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKAEMIA

Abstract

Bone marrow smears from 21 untreated patients with ALL have been morphologically analysed. There was a positive correlation between the percentages of lymphoid cells with amoeboid movement configuration (AMC) and the mitotic indices. A high proportion of cells with AMC seems to indicate a more favourable prognosis in spite of differences in subsequent treatment. It is suggested that studies of the incidence of AMC may serve as a prognostic tool in ALL.