THE CIRCULATORY EFFECT OF DRUG ON LYMPHEDEMA

I Ohara

Abstract


Various kinds of drugs are used to improve the lymphedema
of the extremities. In this report, a dye transducer
was applied on the site of edema of the leg,
foot, or hand and indocyanine green was injected
intravenously. The change of circulating dye was
recorded by means of dye densitometer. The edematous
tissue showed higher dye concentration with
lapse of time, while drugs, i.e., Esberiven®, urokinase,
kallikrein, etc., accelerated the dye dilution. These
drugs have the effect to correct the stagnant microcirculation
to a more steady flow in the region of edema.


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