DIABETIC LYMPHANGIOPATHY. AN OPTICAL AND ELECTRON MICROSCOPIC STUDY

A Kaufmann, B Molnar, C Cracion, A Itcus

Abstract


The lymphatic capillaries in the tegument of the
dorsal side of the leg in patients with diabetes mellitus,
and especially in those with clinically manifested
macroangiopathy, present morphopathological
modifications at the level of the endothelium
and the basal membrane. Ultrastructurally, the modifications
appear as dilatations of the intercellular
space, dislocation or desquamation of the endothelium,
an exaggerated growth of the micropinocytic
vesicles, the appearance of the intracellular vacuoles
and of the lysosomes. These modifications point to
an increase in the endothelium permeability, which
is an important phenomenon in the diabetic microangiopathy.


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