LYMPHOCYTE SUBPOPULATIONS IN HUMAN LYMPH NODES: A NORMAL RANGE

RB Black, AS-Y Leong, PA Cowled, IJ Forbes

Abstract


21 nodes from control subject , 12 normal and 9 howing reactive hyperplasia. Reactive node showed significantly decreased proportion of T lymphocytes (median 44%) and increased proportion of B lymphocytes (median 32 %) when compared with normal nodes (median 68% and 18 %, respectively).  The increase in B lymphocytes was seen in all immunogtobulin classes studied. The values for normal
nodes were comparable with three previous studies of nodes confirmed to be normal by histology . On the other hand, the result from reactive nodes were
similar to the majoritiy of previously published " control" nodes, many of which were histologically abnormal. The importance of ensuring that control
nodes are histologically normal is empha ized by this study.


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