NEW STRUCTURAL DETAILS OF DERMAL LYMPHATIC VALVES AND ITS FUNCTIONAL INTERPRETATION

Judit Daroczy

Abstract


Dermal lymphatics (rat and human) were studied
electronmicroscopically and changes within the lymphatic
wall including neoformation of intralymphatic
valves were followed by serial sections. Two new forms
of intralymphatic valves were observed - unicellular
valve or single endothelial cell extension deep into the
lymphatic lumen and bunch valve, or a connective tissue
core with numerous tip-cells at its cuspidal edge. These
structures functioned as "flap" or "helper" valves and
like inlet (intramural) valves, they were variable structures
appearing and disappearing with changes in the
local interstitial environment. Lymphatic capillaries probably
act as microscopic pistons to pump and suction
lymph fluid in a centripetal direction.


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