THROMBUS FORMATION IN LYMPHATIC VESSELS ASSOCIATED WITH BRUGIA MALAYI

R Fader, A Ewert, D Folse

Abstract


Lymph thrombi within affected afferent lymphatic
vessels of cats infected with Brugia malayi
were examined by scanning electron microscopy.
Thrombi were made up of alternating layers of fibrin
strands and cells, many of which were intact
erythrocytes. The endothelial lining of the vessel wall
near the site of thrombus attachment showed transition
from normal endothelial cells to a flattened syncytium
in which individual endothelial cells could
not be distinguished. Imprints of cells, including
erythrocytes, were visible in the vessel wall at the
point of thrombus attachment. Damage to the endothelial
lining may be a factor in the initiation of
thrombus formation.


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