A NOVEL FLT4 GENE MUTATION AND MR LYMPHANGIOGRAPHY IN A CHINESE FAMILY WITH MILROY DISEASE

Abstract

Milroy disease is a congenital onsetlymphedema linked to FLT4 gene mutationsin the tyrosine kinase domain. So far, a totalof 59 different FLT4 variants have beenidentified. Here, we report a novel FLT4 genemutation in a Chinese family with Milroydisease and present their clinical symptomsand MR lymphangiographic findings.