FACTOR VIII-ASSOCIATED ANTIGEN IN HUMAN LYMPHATIC ENDOTHELIUM

RB Nagle, MH Witte, AP Martinez, CL Witte, MJC Hendrix, D Way, K Reed

Abstract


Lymphatic vascular endothelium both on tissue section and in culture exhibits positivity for Factor VIII-associated antigen although staining is generally less intense and more spotty than in comparable blood vascular endothelium. Lymphatic endothelium also exhibits Weibel-Palade bodies. Neither marker, therefore, reliably distinguishes blood vascular endothelium from lymphatic endothelium.

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