EFFECT OF HALOTHANE ANESTHESIA ON MESENTERIC INTRALYMPHATIC PRESSURE IN THE RAT

T Takeshita, M Kawahara, S Akita, T Moriyama, K Fujii, M Sinozaki, M Morio

Abstract


The effect of halothane on mesenteric intralymphatic pressure was examined in 20 rats. Following administration of 1.5% halothane, lymph pressure decreased from a control value of 7.6 +/- 1.5cmH20 to 3.8 +/- 1.8cmH20. On the other hand, a lower concentration of halothane (1%) did not alter lymph pressure. In conjunction with earlier findings, these data suggest further that lymph propulsion is suppressed during halothane (greater than 1.5%) anesthesia.

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