THE EFFECTS OF MANUALLY APPLIED INTERMITTENT PULSATION PRESSURE TO RAT VENTRAL THORAX ON LYMPH TRANSPORT

Abstract

The present study evaluated the effects of tissue massage on a part of the body remote fromthe region of lymph uptake into the initial lymphatics. Lymph uptake was assessed with afluorescent probe placed in a potential space of the lower extremity of anesthetized femaleSprague-Dawley rats. Tail blood was assayed at intervals over 15 hours for fluorescence. A totalof 63 animals were utilized (treatment = 32 and control = 31). The manipulated group receivedlymph flow enhancing treatment (LFET) five minutes per rat per hour until they were aroused.The control group were left lying prone in cages until a blood sample was taken. The LFETprocedure was bilateral finger pressure applied to the lower ribs of a supine rat followedimmediately by a light tap to the sternum. These maneuvers were repeated for 5 minutes. Therate of appearance of fluorescent probe was greater during the first nine hours of the experimentin the treatment group than in the controls but not at hours 12 and 15. This study demonstratesthat mechanical pressure to body regions physically distant from the location of lymph formationenhances lymph uptake.