LIPOBLASTOMA-LIPOBLASTOMATOSIS ASSOCIATED WITH UNILATERAL LIMB HYPERTROPHY: A CASE REPORT IN A NEWBORN

Abstract

Lipoblastoma (1) is a benign mesenchymaltumor of embryonic adipose tissue, uncommonin infancy. Multicentricity, absence ofa capsuleand histopathology best defines a lipoblastoma(2,3). Synonyms for this lesion are (4)embryonic lipoma, fetal lipoma, lipoblastictumor, and congenital lipomatoid tumor.Lipoblastoma is more common in males(-80%) (5), is usually located in the subcutaneoussoft tissue (benign lipoblastoma) or inthe deep interstitium (benign lipoblastomatosis),or sometimes in all corporeal segments.Primary treatment is complete excision.Relapse is between 14-25%, many of whichare more "mature," and difficult to differentiatefrom lipoma. The differential diagnosisincludes liposarcoma, which is rare under tenyears (6). Radical excision in children isrecommended with relapses, especially withlipoblastomatosis (7). Chromosomal markershelp discriminate between liposarcoma andlipoblastoma (8).